Thursday, January 26th, 2023

 

14.00 – 15.30 Perlan WORKSHOPS – Introduction to the use of high-resolution mass spectrometry coupled with liquid chromatography in qualitative biological and chemical analyzes

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Friday, January 27th, 2023

 

8.00 – 8.15 – REGISTRATION (workshops)

 

8.15 – 10.45 – Bioanalytic WORKSHOPS – Sample preparation – the key to reach the goals; HR MS/MS – MRMhr, DDA or DIA – which way to go and why?

10.45 – 11.00 – BREAK

11.00 – 12.25 – Bruker WORKSHOPS - LIVE training session of Bruker's MetaboScape software

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12.15 – 12.45 – MAIN REGISTRATION

 

12.45 – 13.00 – CONFERENCE OPENING

13.00 – 13.45 – MAIN LECTURE – Nicola Zamboni - Democratization of metabolomics in life and health sciences

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Session 1 – DISEASES

(chairpersons: Magdalena Łuczak, Michał Markuszewski)

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13.45 – 14.15 – L1 – Michał Ciborowski - Serum metabolomics and fecal microbiota analysis in newly diagnosed children with inflammatory bowel disease

14.15 – 14.30 – O1 – Patrycja Kaczara – Pharmacologic modulation of platelet energy metabolism as a way to develop innovative antiplatelet therapies

14.30 – 14.35 – P1 - Agnieszka Karaś – Vascular inflammation inducted by IL-1b modulates metabolism and function in the isolated murine aorta

14.35 – 14.40 – P2 - Marta Tomczyk – Alternations of NAD+ metabolomic footprint in Huntington’s disease

14.40 – 14.45 – P3 - Ewa Paszkowska – Effects of CoQ10 supplementation in statin-treated patients

14.45 – 15.05 – S1 - Bartosz Rasiński – Markers for COVID-19 disease progression: comprehensive LC-MS characterization of the metabolome (Waters)

15.05 – 15.30 – COFFE BREAK

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Session 2 – ORGANS

(chairpersons: Joanna Godzień, Michał Ciborowski)

 

15.30 – 16.00 – S2 - Rafał Szewczyk – Identification of known and unknown compounds by HR LC-MS/MS

16.00 – 16.30 – L2 – Dominika Drulis-Fajdasz – Age-related memory formation defects are accompanied by the metabolic profile

16.30 – 16.45 – O2 - Krzysztof Urbanowicz – High mass and spatial resolution imaging of brain lipids using AP-MALDI-Orbitrap MS

16.45 – 16.50 – P4 - Natalia Pudełko-Malik – Development and validation of a fast, selective and sensitive LC-MS method for quantification of glycogenolysis phosphorylase inhibitor (BAY U6751) in mouse tissues

16.50 – 16.55 – P5 - Joanna Bogusiewicz - Coated blade spray mass spectrometry as a useful tool for rapid analysis in biomedical application

16.55 – 17.00 – P6 - Wioleta Gosk – Targeted metabolomics analysis of aqueous humor in patients undergoing simultaneous bilateral cataract surgery

17.00 – 17.05 – P7 - Karolina Pietrowska – Metabolomic fingerprinting of vitreous humor from patients with epiretinal membrane or molecular hole

17.05 – 17.10 – P8 - Joanna Raczak-Gutknecht – Metabolic profiles of samples from patients with and without atrial fibrillation based on gas chromatography coupled with mass spectrometry

17.10 – 17.15 – P9 - Agata Jędrzejewska – Beneficial effects of nicotinamide riboside on NAD+ metabolome and cardiac function in heart failure rats

17.15 – 17.20 – P10 - Oliwia Król – Alternations of nicotinamide related metabolic pattern in hypertension and heart failure

17.20 – 17.45 – COFFE BREAK

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Session 3 – PLANTS and BACTERIA

(chairpersons: Barbara Pacholczyk-Sienicka, Nicola Zamboni)

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17.45 – 18.15  – L3 - Mariusz Bromke - Metabolomic analysis of a Pseudomonas-resistant versus a susceptible Arabidopsis accession

18.15 – 18.30  – O3 - Natalia Płatosz - Assessing the penetration of red cabbage and aronia anthocyanins and their phase II metabolites through the blood-CSF barrier: A sheep model study

18.30 – 18.45  – O4 - Natalia Drabińska - Comprehensive two-dimensional gas chromatography-time of flight mass spectrometry as a tool for tracking roasting-induced changes in the volatilome of cold-pressed rapeseed oil

18.45 – 18.50 – P11 - Dariusz Kruszka – Effect of DNA methylation inhibitor - zebularine on the Salix Purpurea L. metabolome

18.50 – 18.55 – P12 - Paweł Wityk - Bacterial metabolite isolation and quantification from clinical E. coli cell culture – challenges in sample preparation of UTI and urosepsis strains

18.55 – 19.00  – P13 - Natalia Tyszkiewicz - Identification of biosurfactants produced in microbial fuel cells using LC-MS/MS method

19.00 – 19.05 – P14 - Karolina Mielko – Metabolic response of Acinetobacter Baumannii for aPDT multiple photosensitization

19.40 – 23.00 - DINNER (ODRA CENTRUM, Wybrzeże Słowackiego 5B, 50-406 Wrocław)

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Saturday, January 28th, 2023

 

9.00 – 9.05 – SECOND DAY OF CONFERENCE

 

Session 4 – CANCERS 1

(chairpersons: Karolina Mielko, Stefan Chłopicki)

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9.05 – 9.35 – L4 – Michał Markuszewski - Metabolomics in clinical perspective – analysis of gastrointestinal stromal tumour samples

9.35 – 9.50 – O5 - Anna Wojakowska – Metabolomic profiling of serum exosomes in cancer patients treated by radiotherapy

9.50 – 10.05 – O6 - Julia Siemińska – Urine lipid mediator metabolites associates with endometrial cancer

10.05 – 10.35 – S3 - Mohamed Elsadig - 4D-multiomics – next dimension brings research to a new level (Bruker Daltonics)

10.35 – 11.00 – COFFE BREAK

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Session 5 – CANCERS 2

(chairpersons: Karolina Pietrowska, Wiesław Wiczkowski)

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11.00 – 11.15 – O7 - Joanna Godzień – Phosphocholines oxidation in patients with Non-small-cell lung cancer

11.15 – 11.20 – P15 - Paulina Klimaszewska – Gas chromatography mass spectrometry – based untargeted metabolomics of plasma from papillary thyroid cancer patients

11.20 – 11.25 – P16 - Martyna Jastrzębska – Effect of zinc and polyphenols co-supplementation on the development of breast cancer and urinary lipidomic profile in rats

11.25 – 11.45 – S4 - Paweł Stalica – Metabolomics Research Platforms & Solutions from Shimadzu. From Rapid & Reproducible Blood Plasma Collection to Multi-Omics HRAM/iMS Platform (ShimPol)

11.45 – 12.45 – DEBATE  - Metabolomics - the future perspective (chairperson: Piotr Młynarz)

(Joanna Godzień, Barbara Pacholczyk-Sienicka, Nicola Zamboni, Michał Markuszewski, Michał Ciborowski, Maciej Stopa, Stefan Chłopicki, Wiesław Wiczkowski)

12.45 – 13.30 – LUNCH

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Session 6 – CELLS and BIOINFORMATICS

(chairpersons: Natalia Drabińska, Mariusz Bromke)

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13.30 – 13.45 – O8 - Łukasz Marczak –  Metabolomic status of BY2 cells adapted to long-term osmotic stress

13.45 – 14.00 – O9 - Anna Pieczara - Modified glucose as a sensor to track the metabolism of individual living endothelial cells - observation of the “Raman spectroscopic signature of life”

14.00 – 14.15 – O10 – Dominik Cysewski - Local translation in the synapse - proteomic analysis

14.15 – 14.20 – P17 - Margot Biesemans – Metabolomics analysis of the mitochondrial metabolism after hypoxia and HIF knockdown

14.20 – 14.25 – P18 - Monika Sapeta – Analysis of changes in the cellular metabolome during oxidative stress and the study of the anti-inflammatory properties of curcumin and metformin

14.25 – 14.30 – P19 - Jarosław Chilimoniuk -  Imputomics: imputation of missing values for ‘omics’ data

14.30 – 14.35 – P20 - Adrian Godlewski - A comparison of different machine-learning techniques for the selection of a panel of metabolites allowing early detection of brain tumors

14.35 – 14.45 – AWARDS AND CLOSING